Prevalence of urogenital tuberculosis among HIV patients attaining healthcare at Hoima Regional Referral Hospital. A cross-sectional study.

Authors

  • Alban Byomucunguzi Mildmay School of Allied Health Sciences Author
  • Bwambale Johnson Mildmay School of Allied Health Sciences Author
  • Franscisco Ssemuwemba Mildmay School of Allied Health Sciences Author
  • Hasifa Nansereko Mildmay Institute of Health Sciences Author
  • Anthony Ssekitoleko Author
  • Jane Frank Nalubega Mildmay School of Allied Health Sciences. Author

DOI:

https://doi.org/10.51168/e0kz4h19

Keywords:

Urogenital tuberculosis, HIV-positive patients, Extrapulmonary tuberculosis, Tuberculosis prevalence, TB/HIV co-infection

Abstract

Background:

This study aimed to determine the prevalence of urogenital tuberculosis among HIV-positive patients attending healthcare at Hoima Regional Referral Hospital.

Methodology:

A hospital-based retrospective cross-sectional study design utilizing secondary data was employed. Data were collected from patient medical records, ART clinic registers, and laboratory records of HIV-positive patients. A total of 112 patient records meeting the inclusion criteria were reviewed using a structured data extraction form. Data analysis was performed using SPSS version 26. Descriptive statistics, including frequencies and percentages, were used to summarize the findings, while Chi-square tests were used to determine associations between study variables and urogenital tuberculosis.

Results:

Prevalence of urogenital tuberculosis among HIV-positive patients is 12.5%, with 14 out of 112 patients affected. The prevalence is higher among males (17.0%) than females (9.2%) and is highest among patients aged above 45 years (16.7%). Higher prevalence is also reported among patients from rural areas (14.7%), those who were divorced or separated (20.0%), those with no formal education (25.0%), and unemployed patients (16.3%).

Conclusion:

Urogenital tuberculosis prevalence was high, with higher occurrence among males, older patients, rural residents, and socioeconomically disadvantaged groups. 

Recommendation:

Strengthening routine TB screening among HIV-positive patients, improving early diagnosis of extrapulmonary tuberculosis, increasing access to diagnostic tests such as GeneXpert and urine LAM assays, and enhancing health education and TB/HIV collaborative service.

Author Biographies

  • Alban Byomucunguzi, Mildmay School of Allied Health Sciences

    a student pursuing a diploma in medical laboratory technology.

  • Bwambale Johnson, Mildmay School of Allied Health Sciences

    research supervisor at Mildmay School of Allied Health Sciences.

  • Franscisco Ssemuwemba, Mildmay School of Allied Health Sciences

    research supervisor at Mildmay School of Allied Health Sciences.

  • Hasifa Nansereko, Mildmay Institute of Health Sciences

     research supervisor at Mildmay School of Allied Health Sciences.

  • Anthony Ssekitoleko

    research supervisor at Mildmay School of Allied Health Sciences.

  • Jane Frank Nalubega, Mildmay School of Allied Health Sciences.

    research supervisor at Mildmay School of Allied Health Sciences.

References

1. Broger, T., Nicol, M. P., Székely, R., & others. (2020). Diagnostic accuracy of urine lipoarabinomannan assays for tuberculosis in people living with HIV: A systematic review and meta-analysis. The Lancet Infectious Diseases, 20(7), 806–819. https://doi.org/10.1016/S1473-3099(20)30043-7

2. Cresswell, F. V., Sahr, F., Ggayi, A.-B. M., et al. (2020). Urine lipoarabinannan (LAM) testing for tuberculosis detection among HIV-positive hospitalized patients in Uganda. Clinical Infectious Diseases, 70(12), 2660–2667. https://doi.org/10.1093/cid/ciz704

3. Figueiredo, A. A., Lucon, A. M., & Srougi, M. (2017). Urogenital tuberculosis. Microbiology Spectrum, 5(1). https://doi.org/10.1128/microbiolspec.TNMI7-0015-2016

4. Hirpa, S., Tadesse, T., & Belachew, T. (2022). Gender differences in tuberculosis and HIV co-infection: A systematic review. International Journal of Infectious Diseases, 116, 154–162. https://doi.org/10.1016/j.ijid.2022.01.030

5. Ministry of Health. (2019). Manual for management and control of tuberculosis and leprosy in Uganda.

6. Mohammed, A. Y., Olumuyiwa, A. O., et al. (2018). Extrapulmonary tuberculosis among HIV-infected patients in sub-Saharan Africa: A systematic review and meta-analysis. PLOS ONE, 13(8), e0200915.

7. Muneer, A., Macrae, B., Krishnamoorthy, S., & Zumla, A. (2019). Urogenital tuberculosis—Epidemiology, pathogenesis and clinical features. Nature Reviews Urology, 16(10), 573–598. https://doi.org/10.1038/s41585-019-0228-9

8. Nyatichi, F. O., Amimo, F. A., Nabie, B., & Ondimu, T. O. (2016). Factors contributing to delay in seeking treatment among pulmonary tuberculosis patients in Suneka Sub-County, Kenya. Journal of Health Education Research & Development, 4, 170. https://doi.org/10.4172/2380-5439.1000170

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10. Shah, S., Kabange, L., & Mpunga, J. (2021). Urban–rural disparities in TB-HIV co-infection in the Democratic Republic of Congo. BMC Infectious Diseases, 21(1), 104. https://doi.org/10.1186/s12879-021-05801-1

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13. Zhao, Y., Wang, L., & Zhang, H. (2025). Age and sex distribution of tuberculosis in HIV-positive populations. International Journal of Tuberculosis and Lung Disease, 29(2), 115–123.

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Published

2026-10-09

Issue

Section

Section of peer-reviewed articles

How to Cite

Prevalence of urogenital tuberculosis among HIV patients attaining healthcare at Hoima Regional Referral Hospital. A cross-sectional study. (2026). Journal of Clinical and Diagnostic Medicine Africa, 1(3), 9. https://doi.org/10.51168/e0kz4h19

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