Prevalence and factors contributing to maternal megaloblastic anemia among pregnant women attending Ndejje Health Centre IV in Wakiso District. A cross-sectional study.

Authors

  • Raymond Alex Mwesige Mildmay Institute of Health Sciences Author
  • Hasifa Nansereko Mildmay Institute of Health Sciences Author
  • Francisco Ssemuwemba Mildmay Institute of Health Sciences Author
  • David Kavuma Mildmay Institute of Health Sciences Author
  • Jane Frank Nalubega Mildmay Institute of Health Sciences Author

DOI:

https://doi.org/10.51168/gbg4je91

Keywords:

Maternal megaloblastic anemia, Socio-economic factors, Antenatal care, Folic acid deficiency, Vitamin B12 deficiency, Pregnant women, Ndejje Health Centre IV

Abstract

Background.

Maternal megaloblastic anemia, primarily caused by folic acid and vitamin B12 deficiency, is an important public health concern during pregnancy because it increases the risk of maternal and fetal complications. This study assessed the prevalence and socioeconomic factors associated with maternal megaloblastic anemia among pregnant women attending antenatal care at Ndejje Health Centre IV.

 

Methods.

A descriptive cross-sectional study employing a retrospective review of secondary data was conducted using 163 antenatal records of pregnant women who attended Ndejje Health Centre IV. Data were extracted using a structured checklist, entered into Microsoft Excel, and analyzed using SPSS version 25. Descriptive statistics summarized participant characteristics and prevalence, while Chi-square tests assessed associations between socio-economic factors and maternal megaloblastic anemia at a significance level of p < 0.05.

 

Results.

The prevalence of maternal megaloblastic anemia was 22/163 (13.7%). The majority of pregnant women were aged 20–29 years (44.2%), while 58 (35.6%) were engaged in small businesses. Regarding the study objectives, no statistically significant association was found between age and maternal megaloblastic anemia (χ² = 3.21, p = 0.36). Similarly, education level (χ² = 4.18, p = 0.24) and occupation (χ² = 2.76, p = 0.43) were not significantly associated with the condition.

 

Conclusion.

The condition was not significantly associated with age, education level, or occupation, suggesting that nutritional deficiencies and antenatal care practices may play a greater role than socio-economic factors.

 

Recommendation.

Health facilities should strengthen nutrition education, ensure uninterrupted folic acid supplementation, and promote early and regular attendance at antenatal care.

Author Biographies

  • Raymond Alex Mwesige, Mildmay Institute of Health Sciences

    is a student of a diploma in medical laboratory technology at Mildmay Institute of Health Sciences.

  • Hasifa Nansereko, Mildmay Institute of Health Sciences

    is a research supervisor at Mildmay Institute of Health Sciences.

  • Francisco Ssemuwemba, Mildmay Institute of Health Sciences

    is a research supervisor at Mildmay Institute of Health Sciences.

References

1. Bashir, A., et al. (2021). Study on factors contributing to maternal anemia among pregnant women.

2. Bongomin, F., et al. (2021). Prevalence of anemia among pregnant women in Uganda: A systematic review.

3. Hiraoka, M. (2019). Maternal nutrition, education, and micronutrient deficiencies during pregnancy.

4. Kassa, G., et al. (2022). Factors associated with maternal anemia during pregnancy.

5. Keats, E. C., et al. (2021). Micronutrient deficiencies and maternal anemia during pregnancy.

6. Kibret, K., et al. (2021). Education and nutritional status among pregnant women.

7. Mezzano, D., et al. (2022). Effects of folate and vitamin B12 deficiency on pregnancy outcomes.

8. Nakimuli, A., et al. (2023). Prevalence of maternal megaloblastic anemia among pregnant women in Uganda.

9. Nankinga, O., & Aguta, D. (2019). Macrocytic anemia among pregnant women in Uganda.

10. O'Leary, F., & Samman, S. (2018). Vitamin B12 in pregnancy and maternal health.

11. Smith, J., et al. (2022). Folate and vitamin B12 deficiency among pregnant women in sub-Saharan Africa.

12. Uganda Ministry of Health. (2022). Uganda Clinical Guidelines. Kampala, Uganda: Ministry of Health.

13. World Health Organization. (2021). Anaemia in women and children. Geneva, Switzerland: World Health Organization.

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Published

2026-10-21

Issue

Section

Section of peer-reviewed articles

How to Cite

Prevalence and factors contributing to maternal megaloblastic anemia among pregnant women attending Ndejje Health Centre IV in Wakiso District. A cross-sectional study. (2026). Journal of Clinical and Diagnostic Medicine Africa, 1(3), 8. https://doi.org/10.51168/gbg4je91

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